Hydrophobic Effect

A. Lee, K. A. Mirica, and G. M. Whitesides. 2011. “The Influence of Fluorocarbon and Hydrocarbon Acyl Groups at the Surface of Bovine Carbonic Anhydrase II on the Kinetics of Denaturation by Sodium Dodecyl Sulfate”. J. Phys. Chem. B, 115, Pp. 1199-1210

J. Mecinovic, P. W. Snyder, K. A. Mirica, S. Bai, E. T. Mack, R. L. Kwant, D. T. Moustakas, A. Herous, and G. M. Whitesides. 2011. “Fluoroalkyl and Alkyl Chains Have Similar Hydrophobicities in Binding to the ‘Hydrophobic Wall’ of Carbonic Anhydrase”. J. Amer. Chem. Soc., 133, Pp. 14017-26

P. W. Snyder, J. Mecinovic, D. T. Moustakas, S. W. Thomas, M. Harder, E. T. Mack, M. R. Lockett, A. Heroux, W. Sherman, and G. M. Whitesides. 2011. “Mechanism of the Hydrophobic Effect in the Biomolecular Recognition of Arylsulfonamides by Carbonic Anhydrase”. Proc. Natl. Acad. Sci. USA, 108, Pp. 17889-94

B. F. Shaw, G. F. Schneider, H. Arthanari, M. Narovlyansky, D. T. Moustakas, A. Durazo, G. Wagner, and G. M. Whitesides. 2011. “Complexes of Native Ubiquitin and Dodecyl Sulfate Illustrate the Nature of Hydrophobic and Electrostatic Interactions in the Binding of Proteins and Surfactants”. J. Amer. Chem. Soc., 133, Pp. 17681-95

K. A. Mirica, M. R. Lockett, P. W. Snyder, N. D. Shapiro, E. T. Mack, S. Nam, and G. M. Whitesides. 2012. “Selective Precipitation and Purification of Monovalent Proteins Using Oligovalent Ligands and Ammonium Sulfate”. Bioconjugate Chem., 23, Pp. 293-99

B. F. Shaw, G. F. Schneider, and G. M. Whitesides. 2012. “Effect of Surfactant Hydrophobicty on the Pathway for Unfolding of Ubiquitin”. J. Amer. Chem. Soc., 134, Pp. 18739-45

M. R. Lockett, H. Lange, B. Breiten, A. Heroux, W. Sherman, D. Rappoport, P. O. Yau, P. W. Snyder, and G. M. Whitesides. 2013. “The Binding of Benzoarylsulfonamide Ligands to Human Carbonic Anhydrase Is Insensitive to Formal Fluorination of the Ligand”. Angew. Chemie., 125, Pp. 7868-71

P. W. Snyder, M. R. Lockett, D. T. Moustakas, and G. M. Whitesides. 2013. “Is It the Shape of the Cavity, or the Shape of the Water in the Cavity?”. European Physical Journal Special Topics, 223, Pp. 853-91

B. Breiten, M. R. Lockett, W. Sherman, S. Fujita, M. Al-Sayah, H. Lange, C. M. Bowers, A. Heroux, G. Krilov, and G. M. Whitesides. 2013. “Water Networks Contribute to Enthalpy Enthropy Compensation in Protein-Ligand Binding”. J. Amer. Chem. Soc., 135, Pp. 15579-84

K. Kang, J-M. Choi, J. M. Fox, P. W. Snyder, D. T. Moustakas, and G. M. Whitesides. 2016. “Acetylation of Surface Lysine Groups of a Protein Alters the Organization and Composition of Its Crystal Contacts”. J. Phys. Chem. B, 120, Pp. 6461-68